Teaching/Research activities
CURRENT RESEARCH ACTIVITIES AT THE INSTITUTE
The Institute has Eleven Units headed by academics of repute in various disciplines. The details of the activities of each Unit are as follows:
1. MEDICAL GENETIC RESEARCH UNIT (MGRU)
HEAD OF UNIT - PROFESSOR ADEYINKA G. FALUSI
The activities of the Unit include:
(i) Population genetics of sickle cell disease, the thalassaemias and other factors, which modify the pathology of these diseases.
(ii) Identification of genetic factors modifying the incidence and prognosis of Hypertension, Pre-eclampsia/Eclampsia and Diabetes.
(iii) Molecular Epidemiology of the genetic markers, which affect the prognosis resistance and treatment of malaria.
(iv) Molecular markers of resistance to chloroquine (Pfrudr 1 and Pfcrt genes) and sulphadoxine Pyrimethamine (DHFR and DHFR genes).
(v) invivo and invitro evaluation of antimalaria drug sensitivity
(vi) Antimalaria drug disposition and Kenetics.
(vii) Awareness programme of Education, Genetic counseling and diagnosis of the haemoglobinopathies in Nigerians.
These activities are carried out in collaboration with other departments such as Medicine, Pharmacy, Institute of Child Health and other Institutions such as Institute for Tropical Medicine, Berlin.
Staff List of the Unit
Prof. Adeyinka G. Falusi – Genetics of Haemoglobinopathies
Dr O.G. Ademowo – Genetics of Malaria
Dr. Funmi Olopade (Adjunct) – Genetics of Breast cancer
Dr. A.I. Ojesina - (PG Student/ Research Assistant - (Study Leave)
Dr. C.P. Babalola - Genetics of Drug Kinetics
Mr. A. Odetunde - Technologist I
2. MALARIA RESEARCH UNIT (MRU)
HEAD OF UNIT - PROFESSOR A.M.J. ODUOLA
The Malaria Research Unit expanded into a larger malaria research group and has its area of Research focus:
Studies on Pharmacological and Clinical Efficacy of antimalarial Drugs.
Basic Laboratory Research on Chemotherapy, Parasitology and Biology of Malaria Parasites.
Application of Social Sciences in Tropical Disease Control.
These activities are carried out in collaboration with other departments viz. Pharmacology & Therapeutics, Zoology, Preventive and Social Medicine and other Research Institutes in Nigeria and in the United States of America, Malaysia and Ghana.
The WHO/TDR sponsored linkage programme is coordinated by this Unit in collaboration with the National Institute for Medical Research (NIMR) Yaba, Lagos and the University of Nigeria, Enugu. The Satelife Corporation of the United States and WHO/TDR provide Technical Assistance for communication among the linkage institutions.
Academic Staff List of the Unit
Prof. A.M.J. Oduola
Prof. Akin Sowunmi
Prof.J. Adeniyi
Prof. O. Oladepo
Dr. Catherine Falade
Dr. Edith Ajaiyeoba
Dr. Grace Olusola Gbotosho
Dr. Christian Happi
<!- 3 HEALTH AND INFORMATION SYSTEMS RESEARCH AND TRAINING UNIT (H&ISRTU)
HEAD OF UNIT - PROFESSOR A. O. ODEJIDE (ADJUNCT STAFF)
This is a multi-disciplinary group consisting of health workers, biostatisticians, policy makers and social scientists.
The activities of the Unit include:
(i) Development of Disability Assessment Scheme (WHO DAS II).
(ii) International Classification of Impairments, Disabilities and Handicaps (ICIDH).
(iii) Rapid Assessment of the operations of Primary Health Care System in Nigeria.
(iv) National Survey of Substance Abuse behaviour among children and young adults in collaboration with ATRC Incorporation, Maryland, and USA a branch of Awele Foundation, Nigeria.
(v) Life skills education in collaboration with the International Centre for Alcohol Policy (ICAP) USA.
4. ENVIRONMENTAL HEALTH RESEARCH AND SERVICE UNIT (EHRSU)
HEAD OF UNIT - PROFESSOR M.K.C. SRIDHAR
Various projects which the Unit has focused on include:
(i) Training of Nigerian and International Postgraduate Students for Research in Environmental Health, Toxicology and Environmental Epidemiology.
(ii) Organizing workshops and short courses on Environmental Health, Hazardous and Biomedical Wastes.
(iii) Research/services on water quality, waste characterization, EIA, EA Waste Management and recycling UNICEF and NGOs are (recycling) collaborating in these activities.
5. EPIDEMIOLOGY & BIOSTATISTICAL RESEARCH AND SERVICES UNIT (EBRSU)
HEAD OF UNIT - PROFESSOR E .A. BAMGBOYE (ADJUNCT STAFF)
(i) Provides training programmes to help capacity building in research methodology, epidemiology, biostatistics and computing in medical sciences.
(ii) Provides consultancy services to Faculty members on the designs, conduct, analysis and interpretation of data on regular basis.
(iii) Conducts research (in collaboration with other medical scientists) in development of morbidity and mortality indicators related to prevailing health problems in Nigeria and evaluation of health programmes.
(iv) Carries out research on the epidemiology of specific disease of public health impor-tance e.g. AIDS, Asthma and Malaria.
(v) Conducts the IMRAT Epidemiology and Medical Statistic’s Clinic.
6. PHARMACEUTICAL SCIENCES AND SERVICE UNIT (PSSU)
HEAD OF UNIT - DR. EDITH AJAIYEOBA (ADJUNCT STAFF)
The Unit with the cooperation of the Faculty of Pharmacy is involved in the:
(i) Establishment of standard Ethno-medical Herbarium.
(ii) Extraction, isolation and development of pure compounds having anti-microbial, anti-tumor, anti-malaria and anti-viral properties from plants.
(iii) Formulation of active compounds into dosage forms.
The Unit collaborates with donor agencies both nationally and internationally.
7. CANCER RESEARCH AND SERVICES UNIT (CRSU)
HEAD OF UNIT - PROFESSOR BOLA O.A... OSIFO (ADJUNCT STAFF)
This Unit handles two separate Federal Government sponsored projects:
(i) Cancer Screening Project
This project is involved in diagnosis, monitoring and screening for various types of cancers in our environment.
(ii) Neonatal Hypothyroidism Screening Project
This project is set out to screen neonates for hypothyroidism. The two projects receive financial support from the Federal Government of Nigeria while reagents and equipment are supplied by the International Atomic Energy in Vienna, Austria
8. BEHAVIOURAL AND SOCIAL SCIENCES RESEARCH UNIT (BSSRU)
HEAD OF UNIT - PROFESSOR J.D. ADENIYI (ADJUNCT STAFF)
The Unit is responsible for research on behavioural socio-cultural and economic aspects of health and diseases including – Acquired Immunodeficiency Syndrome (AIDS), Tuberculosis & other poverty related disease, population studies, socio-pathological conditions, geriatric diseases and malaria.
These activities are carried out with various Faculties in the University and research from other institutions.
9. INSTITUTIONAL REVIEW BOARD (IRB)
CHAIR UI/UCH IRB - PROFESSOR ADEYINKA G. FALUSI
IRB00002499-U Ibadan IRB #1
Parent Organization: IORG0001987
Located at: IMRAT College of Medicine, UCH, IBADAN, NIGERIA
Date of International Registration: May 13, 2002 – May 13, 2005
FWA number: FWA00003094
Mission: Our mission is to upgrade the UI/UCH Joint Ethical Committee to the UI/UCH Ethical Reviews Committee of an International standard.
Goals
(i) To set up an appropriate Ethical Reviews Committee comprising of Health and legal professionals from diverse specialties and laymen capable of dealing with the complex, numerous collaborative proposals which are sent in for approval.
(ii) To register the members of the UI/UCH Reviews Board with the International Review Board.
(iii) To register the UI/UCH Review Board with the Federal Wide Assurance.
(iv) To source funding – locally and internationally for the establishment of and maintenance an adequate secretariat.
(v) To commence a Training Programme for:
(a) All members of newly constituted Reviews Board
(b) Principal Investigators submitting a proposal for Human Subjects Projects.
(c) Researchers in the University of Ibadan.
(d) Researchers from other allied tertiary institutions in Nigeria.
Membership
Prof. Adeyinka G. Falusi B.Sc., M.Phil, Ph.D (Ib.) - Director, (IAMRAT) – Chairperson UI/UCH IRC
Dr. A. O. Malomo MBBS (Ib), FWACS - CMAC, UCH
Prof. E.A. Bamgboye B.Sc. (Lagos) MSc (Med Stat) (Lond) PHD(Lond) MIS (UK) FSS(Lond)Biostatistian (Department of EMSEH)
Barrister O. Aluko Board of IAMRAT nominee - (Aluko Chambers)
Dr. A.A. Oni MBBS (Ib) MSc (Ib) FWACP - Dept. of Medical Microbiology, Faculty of Basic Med. Sci. Rep
Prof.W.A.Shokunbi Haematology Dept, Faculty of Basic Medical Sciences.
Dr. Millicent O. Obajimi BSc. (Lagos) MBBS (Ib) DMRD (UK), FWACS, FMCR (Nig) Dept. of Radiology, Faculty of Clinical Sciences Rep.
Mr.T.O.Ogundiran. MBBS
FWACS, FRCS -
Surgery Dept.,
Fac. of Clinical Sciences.
Dr. J.A. Ajuwon – BSc (Lagos) MPH (Ib) PhD - Dept of Health Prom. & Educ. Faculty of Public Health Rep.
Dr. Eme T. Owoaje - MBBS (Ib) FMCPH, PHD - Dept. of Community Medicine Faculty of Public Health Rep.
Dr Chinedum .P. Babalola - B. Pharm., M.Sc. , Ph.D. (Ife) M.P.S.M. - Dept of Pharm. Chem Faculty of Pharmacy Rep.
Dr. Edith O. Ajaiyeoba - BSc, MSc PHD (Ib) - Dept. of Pharmacognosy, Faculty of Pharmacy Rep.
Prof.J.O.Lawoyin.
Oral Pathology Dept.,
Faculty of Dentistry
Prof. Gbemisola Oke.
Preventive Dentistry,
Faculty of Dentistry
Mrs. E.S. Olarinde.
Dept. of public Law,
Fac. Of Law Rep.
Dr. B.A. Odaibo - BSc (Benin) MSc, PhD (Ib) - Zoology Dept. U.I. Faculty of Science Rep.
Dr. Oka Obono - Sociology Dept. U.I, Faculty of the Social Sciences.
Mr. O. B. Shittu. MBBS (Ib)
FWACS, FRCS (Eng) -
Surgery Dept UCH -CMAC Rep.
Dr. O.M. Akinosun
Rep. of CMAC, UCH, Ibadan
Mrs. Olufunke Adetona - (Female Layperson) - Teacher
Mr. O. A. Famosinpe - (Male Layperson) – Agriculturist, retired
Mr.O.O. Afolabi (S/C’s Office) - Secretary.
Other Members include:
Dr. Catherine O. Falade - MBBS (Ib) FMCP (Nig) FWACP - Dept. of Clinical Pharmacology
Dr. A.S. Jegede - BSc. MSc (Ife) PhD (Ib) - Dept of Sociology UI
Dr.A.O. Arowojolu- Dept of Obstetrics & Gynaecology
Mrs. Helen A. Oduntan - MPSN, Pharmacy Dept. UCH.
To a large extent these goals are currently being met. Training Workshops are regularly organized by the IRB. For example the IRB with APIN jointly organized the Bioethics Workshop on Health Research from August 27th – September 1st 2003. IRB also jointly organized with Falk Clinical Cancer Trust, the Workshop on Conflict of Interest in Biomedical Research - January 8th 2004.
10 BIOETHICS RESEARCH UNIT (BRU)
HEAD - PROF. ADEYINKA G. FALUSI
Bioethics Research Unit is a new unit with the Objectives to:
(i) Develop a curriculum for a Certificate Course in Bioethics.
(ii) Develop Postgraduate Diploma Course in Bioethics.
(iii) Incorporate a Bioethics programme into the GES curriculum for undergraduates at University of Ibadan.
(iv) Organise Research on topical issues in Bioethics in Nigeria.
(v) Organise National/International quarterly Seminars in specific Disciplines of Bioethics such as HIV/AIDS, Cancer, Malaria, Genome Studies and Social Science issues.
(vi) Develop training modules for Institutional Review Boards (IRBs) Chairman and members in Nigerian Tertiary Institutions and Non-Governmental Organisations (NGOs).
(vii) Source funding for Bioethics Research from International Organisations and Funding Agencies.
To facilitate these programmes a Core of Bioethics Staff consisting of multidisciplinary team is in place. These are from the Clinical Sciences, Law, Social Sciences, Nursing and Biostatistics reflecting the coordinated activities involved in the use of human subjects in Biomedical research. Our external members, National and International are also available. Pioneers in the Unit include:
1. Professor Adeyinka G. Falusi - IMRAT Director, CHAIR UI/UCH IRC.
2. Dr. Sola Olopade - Adjunct Staff (USA).
3. Dr. A. Ajuwon - Health Promotions Dept.
4. Mrs. E. Olarinde - Law Department
Members from other disciplines will gradually be incorporated into the Unit as appropriate.
A library of Bioethics is already coming on board for the programme.
The programme will enhance capacity building in Bioethics as it develops the human skills with effective utilization of professional resources and technical expertise in the use of human subjects in patient care and research at the University of Ibadan and also in Nigerian Tertiary Institutions in general.
11. AFRICAN JOURNAL OF MEDICINE AND MEDICAL SCIENCES
The African Journal of Medicine and Medical Sciences (AJMMS) came into existence in 1970 with its first publication in 1971. The founding editor was Professor A Olufemi Williams. The Journal is jointly owned and published by the College of Medicine, University of Ibadan, Ibadan and the University College Hospital, (UCH), Ibadan, Nigeria. Its Secretariat is located in the Institute for Advance Medical Research and Training (IAMRAT), College of Medicine, University of Ibadan, Nigeria.
AJMMS is published quarterly; four issues form one volume. It publishes expertly reviewed articles in medicine and medical sciences with particular emphasis on health problem peculiar to Africa. Manuscripts are received for publication not only in Nigeria, but also from African countries, as well as Asia, Europe and North America. Likewise, the journal enjoys a wide spectrum of readership from all over time world.Apart from quarterly publications of the Journal, AJMMS had published a supplementary edition on Malaria. Presently, efforts are on towards publishing another Supplementary issue on HIV/AIDS as well as a book on Hypertension.
Grant
Recently, the Journal received a financial support to publish an edition of the Journal from Publication of Learned Journals Fund of the Postgraduate School of the University of Ibadan, Ibadan.
Present staff list of the journal
1. Professor (Mrs.) Yetunde A Aken’Ova – Editor – in - Chief
2. Professor O. Ogunniyi – Assistant Editor – in – Chief
3. Professor O.D. Olaleye – Assistant Editor – in - Chief
Editorial Assistants
4. Professor O.A. Itiola
5. Dr. A. Arije
6. Dr. J.O. Lawoyin
7. Dr. (Mrs.) Taiwo Lawoyin
8. Dr. C.A. Adebamowo
9. Mr. T. Alonge
10. Mr. E. Olapade-Olaopa
11. Dr. Y. Raji
12. Dr. (Mrs.) K. Ajaiyeoba
13. Dr. E.O. Farombi
Secretariat Staff:
14. Mr. ‘Bukola Oyejide – Business Manager
15. Mr. Adegboyega M. Sodiya
16. Mr. Samuel Adekunle
17. Mr. G A Atolagbe
Subscription orders are welcomed from various subscribers (Institution & Individual) to the Journal. The overseas subscription fee for Institutions and Organizations is $250.00 (US dollar) and $200.00 for individuals. The subscription price for local subscribers is available on a special form at the Editorial Office on request. Back issues are currently available upon request.
Companies and organizations are invited to take advantage of the Journal to advertise their products and services. More so, the journal is widely circulated in the medical circles throughout the world. Consequently, your products or services will enjoy the widest publicity that will enhance their promotion. The advert rate depends on its location in the issue.
Orders for subscription (current and back issues) advertisement and all other business correspondence, including orders for Off-prints should be forwarded to The Business Manager, Attention ‘Bukola Oyejide at the Editorial office, African Journal of Medicine and Medical Sciences, Institute for Advance Medical Research and Training (IAMRAT), College of Medicine, University of Ibadan, Ibadan, Nigeria.
Telephone: 234-02-2414578, 2413324, 2410083 Ext. 3314, 2497.
Fax: 234 – 02 – 2411768.E-mail: afrijmed@comui.ng.edu; afrijmed@yahoo.com
4. CLINICAL ACTIVITIES
A number of Clinical activities in the management of health and disease are carried out. These include:
- Malaria
- Sickle Cell Disease
- Nutritional Deficiency
- Psychological Disorders
- Substance Abuse
5. NOTEABLE EVENTS AND ACHIEVEMENTS
§ IMRAT – Malaria Unit was recognized by UNDP/World Bank/WHO Special Programme for research and Training in Tropical Diseases (TDR) for its excellent work on malaria. The Unit was cited in the TDR brochure of Research Capacity building in developing countries in the year 2003.Malaria Research headed by Prof. M.J. Oduola has currently been designated one of the five African centres to participate in the WHO MIM/TDR anti-malaria drug resistance network in the year 2002. (Sponsorship is from the task force on malaria research on Anti-malaria drugs in Africa).
6. OTHER SIGNIFICANT EVENTS
IMRAT Postgraduate Monthly Seminar Series now resuscitated.
1st Titled “International Mandate in Human Subject Research” Prof. Adeyinka G. Falusi. August 14, 2003.
2nd Titled “A Global Scenerio on Ecosanitation” Prof. M. K. C. Sridhar. Sept 11, 2003.
3rd Titled “Nigeria Ethnomedicine and Intellectual Property Right in Anti-malaria Drug Development” Dr. Edith O. Ajaiyeoba. Oct 16th, 2003.
4th Titled “Research Techniques in Social Marketing” Dr. Virgie Capo- Chichi. November 11, 2003.
5th Titled “The G6PD Gene of Plasmodium Falciparium: Laboratory and Clinical Aspects” Prof. O. Sodeinde. December 11, 2003.
6th Titled “On a Starry Night: The Problems that Lit my Way” Prof. Mark Nwagwu. March 9, 2004.
7th Titled “Drugs: From the body to the test tube and from the test tube to the bug. – Dr. Chinedum P. Babalola – May 11, 2004.
8th Titled “The Soya Bean and its Potential Roles in Cancer Prophylaxis” Mr. O. Oyetunde. June 10, 2004.
9th Titled “Calcium Signalling: Implication in Chloroquine resistance in Malaria Treatment” Dr. O. M Bolaji July13, 2004.
10th Titled “Nigerian Breast Cancer: A Molecular Characterization” Dr. Francis Ikpatt February 15, 2005
11th Titled “The Malaria War: Who is winning?” - Dr. O.G Ademowo March 17, 2005
Workshop on “Conflict of Interest in Biomedical Research” jointly organized by IMRAT, UI/UCH IRB, NIBIN and FALK Cancer Trust of the USA 8th January, 2004.7. ACADEMIC AWARDS RECEIVED BY STAFF TO DATE
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L’OREAL/UNESCO AWARD FOR OUTSTANDING WOMAN IN SCIENCE (Africa – 2001). An Award for 5 Women Scientists in the 5 continents of Africa, Asia, North America, Europe and Latin America at the UNESCO Headquarters, Paris, France. (Feb. 2001) – Adeyinka G. Falusi
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L’OREAL/UNESCO RESOURCE PERSON for nomination of women in science for the Life Sciences in 5 continents of Africa, Asia, North America, Europe and Latin America ( Feb. 2001 to date) – Prof. Adeyinka G. Falusi
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UNESCO RESOURCE PERSON for the search and nomination for L’OREAL/UNESCO YOUNG WOMEN SCIENTISTS GRANTS AWARDS for Africa (April 2002 to date) – Adeyinka G. Falusi
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RARE GEMS AWARD in the category of Science and Technology by the Centre for Development and Population Activities (CEDPA) and Women’s Optimum Development Foundation (WODEF) – 8th March, 2003). – Adeyinka G. Falusi.
8. RESARCH GRANTS RECEIVED
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TDR Research Grant for Molecular Studies in Chloroquine resistance in malaria parasite worth $30,000 received – Dr. O. G. Ademowo of the Molecular Genetic Research Unit in 2002.
§ WHO/TDR antimalarial drug resistance network project. Sponsored by WHO/TDR.
§ Epidemiology of Congenital malaria. Sponsored by ARCH/SAID.
§ Molecular epidemiology of drug resistance malaria and tuberculosis. Sponsored by International Agency for Atomic Energy. Antimalarial Drug Therapeutic Efficacy Tests sponsored by WHO/Federal Ministry of Health.
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§ MIM Research Grant for Home Management, International and Phytomedicine of malaria with $90,000 Annual Grant received in the year 2002 – Prof. J. D. Adeniyi, Prof. O. Oladepo and Dr. E. Ajaiyeoba.
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EMSEH Masters Programme: Masters Programme in Biostatistics and Epidemiology received a support from the Human Reproductive Programme of the WHO with an - annual subvention of $50,000. Studies from the African region – Nigeria, Zimbabwe, Ghana, Cameroon, etc. are trained in the programme - E.A.Bamgboye - IMRAT Adjunct Staff.
9. BENEFACTIONS
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European Commission (INCO) – Dev.) donation of Laboratory Equipment worth a total of $40,000 was received in May 2001 by Dr. O. G. Ademowo of the Genetic Research Unit of the Institute.
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Falk Cancer Trust of the United State of America donated a sum of $20,000 through Professor Adeyinka G. Falusi – Director of IMRAT and Chairperson of UI/UCH Institutional Review Board as “Seed Grant” for setting up a Secretariat of an international standard at the Institute for Advanced Medical Research and Training for the UI/UCH Institutional Review Committee 2002/2003.
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A Second year donation of $55,000 from Falk Cancer Trust for the UI/UCH IRC, a Cancer and an Ethics Research Workshop to be organized by the College of Medicine through the Chairperson UI/UCH IRC – Professor Adeyinka G. Falusi for the period of 2003-2004.
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Alexander von Humboldt Foundation donation of Equipment worth 45,000 EUROS was received in October 2002 by Dr. O. G. Ademowo of the Genetic Research Unit of the Institute.
10. FUTURE GOALS
The plan is to strengthen and expand our objectives and activities to enable the Institute attain its expected position as a National centre for research and training in the country.
The future goals are:
(a) Strengthening of manpower development which includes training of research investigators, students at postgraduate level and health professionals from all parts of the country.
(b) Serving as the research-coordinating centre for tertiary institutions and government parastatals throughout the country.
(c) Collating and dissemination of research findings through appropriate media to implementing bodies such as industries, private sector, policy makers and the general public.
(d) To continue to collaborate and link other research scientist with national and international funding agencies.
